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Jikai Xu Selected Research

Cognitive Dysfunction

1/2023Okanin from Coreopsis tinctoria Nutt. alleviates cognitive impairment in bilateral common carotid artery occlusion mice by regulating the miR-7/NLRP3 axis in microglia.
5/2022Triad3A-Dependent TLR4 Ubiquitination and Degradation Contributes to the Anti-Inflammatory Effects of Pterostilbene on Vascular Dementia.
1/2021Pterostilbene Alleviates Aβ1-42 -Induced Cognitive Dysfunction via Inhibition of Oxidative Stress by Activating Nrf2 Signaling Pathway.
1/2016Xanthoceras sorbifolia extracts ameliorate dendritic spine deficiency and cognitive decline via upregulation of BDNF expression in a rat model of Alzheimer's disease.

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Jikai Xu Research Topics

Disease

5Ischemic Stroke
09/2023 - 06/2020
4Cognitive Dysfunction
01/2023 - 01/2016
3Alzheimer Disease (Alzheimer's Disease)
03/2024 - 01/2016
3Inflammation (Inflammations)
10/2023 - 05/2022
3Reperfusion Injury
09/2023 - 06/2020
3Brain Ischemia (Cerebral Ischemia)
09/2023 - 06/2020
2Stroke (Strokes)
01/2023 - 10/2019
1Cerebral Infarction
12/2022
1Ischemia
12/2022
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
12/2022
1Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy)
05/2022
1Infarction (Infarctions)
06/2020
1Brain Injuries (Brain Injury)
10/2019
1Memory Disorders (Memory Loss)
05/2019
1Dehydration (Water Stress)
03/2018
1Rheumatic Diseases (Rheumatism)
01/2016
1Dementia (Dementias)
01/2016

Drug/Important Bio-Agent (IBA)

5pterostilbeneIBA
03/2024 - 06/2020
2dragon's bloodIBA
10/2023 - 12/2022
1isorhapontigeninIBA
09/2023
1okaninIBA
01/2023
1NLR ProteinsIBA
01/2023
1InflammasomesIBA
01/2023
1loureirin CIBA
12/2022
1Amyloid (Amyloid Fibrils)IBA
01/2021
1Therapeutic UsesIBA
09/2020
1LipopolysaccharidesIBA
09/2020
1AlkaloidsIBA
10/2019
1hasubananIBA
10/2019
1xanthocerasideIBA
05/2019
1OxidesIBA
03/2018
1QuartzIBA
03/2018
1Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2016
1Proteins (Proteins, Gene)FDA Link
01/2016
1rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA
01/2016

Therapy/Procedure

2Traditional Medicine (Folk Remedies)
10/2019 - 01/2016
1Therapeutics
06/2020